Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | FABP2 | P12104 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11750825 | 0.90 | MAPK14 (0.41) | MAPK14MAPK13MAPK12MAPK11ADORA2A | |
| SCHEMBL11751581 | 0.85 | MAPK14 (0.49) | MAPK14ADORA2ACARM1MEN1KMT2A | |
| SCHEMBL11751670 | 0.85 | ADORA2A (0.42) | MAPK14MAPK13MAPK12MAPK11ADORA2A | |
| SCHEMBL11750246 | 0.85 | MAPK14 (0.52) | MAPK14ADORA2ALTB4RPTGS1PTGS2 | |
| SCHEMBL11752080 | 0.83 | ALDH1A1 (0.45) | MAPK14ADORA2AMEN1AKR1C3AKR1C2 | |
| SCHEMBL11749673 | 0.81 | MAPK14 (0.53) | MAPK14ADORA2ACARM1MEN1KMT2A | |
| SCHEMBL11753979 | 0.80 | MAPK14 (0.47) | MAPK14ADORA2AMEN1KMT2A | |
| SCHEMBL11749158 | 0.80 | MAPK14 (0.47) | MAPK14ADORA2AMEN1KMT2A | |
| SCHEMBL11748061 | 0.79 | MAPK14 (0.50) | MAPK14ADORA2ACARM1MEN1KMT2A | |
| SCHEMBL11752064 | 0.79 | ADORA2A (0.55) | MAPK14ADORA2ACARM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |