Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.69 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | SCN1A | P35498 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11752384 | 0.87 | SIGMAR1 (0.64) | SIGMAR1SLC2A1HTR1AADRA1AADRB2 | |
| SCHEMBL11751756 | 0.87 | SIGMAR1 (0.67) | SIGMAR1SLC2A1HTR1AADRA1AADRB2 | |
| Hydrochloric Acid SCHEMBL11755461 | 0.86 | SIGMAR1 (0.66) | SIGMAR1SLC2A1HTR1AADRA1AADRB2 | |
| SCHEMBL11760340 | 0.85 | SIGMAR1 (0.64) | SIGMAR1SLC2A1HTR1AADRA1AADRB2 | |
| SCHEMBL11795052 | 0.84 | SIGMAR1 (0.74) | SIGMAR1SLC2A1HTR1AADRA1AADRB2 | |
| SCHEMBL19505655 | 0.83 | SIGMAR1 (1.00) | SIGMAR1SLC2A1HTR1AADRA1AADRB2 | |
| Hydrochloric Acid SCHEMBL11801880 | 0.82 | SIGMAR1 (0.72) | SIGMAR1SLC2A1HTR1AADRA1AADRB2 | |
| Fenalcomine SCHEMBL25623 | 0.81 | SIGMAR1 (0.71) | SIGMAR1SLC2A1HTR1AADRA1AADRB2 | |
| Hydrochloric Acid SCHEMBL8093842 | 0.81 | SIGMAR1 (0.97) | SIGMAR1SLC2A1HTR1AADRA1AADRB2 | |
| Fenalcomine SCHEMBL364879 | 0.81 | SIGMAR1 (0.69) | SIGMAR1SLC2A1HTR1AADRA1AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4038319-A | SUBSTITUTED PHENOXYALKYLAMINES, PROCESS FOR THEIR PREPARATION AND APPLICATIONS THEREOF | LABORATOIRES LAROCHE NAVARRON (FR) | 1977-07-26 | — | — | US | disclosed |