Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11755375 | 0.91 | SLC6A2 (0.41) | CES1HRH1SLC6A2CHRM1SLC6A4 | |
| SCHEMBL11758970 | 0.88 | SLC6A2 (0.33) | CES1HRH1SLC6A2CHRM1SLC6A4 | |
| SCHEMBL11757344 | 0.88 | KCNA3 (0.40) | HRH1SLC6A2CHRM1SLC6A4DRD2 | |
| SCHEMBL11758967 | 0.88 | SLC6A2 (0.33) | CES1HRH1SLC6A2CHRM1SLC6A4 | |
| SCHEMBL11757352 | 0.88 | KCNA3 (0.40) | HRH1SLC6A2CHRM1SLC6A4DRD2 | |
| SCHEMBL11752852 | 0.87 | HTR1A (0.37) | HRH1SLC6A2CHRM1SLC6A4DRD2 | |
| SCHEMBL11752846 | 0.87 | HTR1A (0.37) | HRH1SLC6A2CHRM1SLC6A4DRD2 | |
| SCHEMBL11755077 | 0.83 | HRH1 (0.53) | CES1HRH1SLC6A2CHRM1SLC6A4 | |
| SCHEMBL11763198 | 0.80 | MEN1 (0.38) | HRH1SLC6A2CHRM1SLC6A4DRD2 | |
| SCHEMBL11757819 | 0.80 | POLB (0.35) | HRH1SLC6A2CHRM1SLC6A4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4003915-A | ANTICONVULSANTS, PARKINSON*S DISEASE | HOFFMANN-LA ROCHE INC. (US) | 1977-01-18 | — | — | US | disclosed |