Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.31 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3839159 | 0.74 | PDE10A (0.34) | PDE10A | |
| SCHEMBL251411 | 0.69 | MAPKAPK2 (0.36) | PDE10A | |
| SCHEMBL6166412 | 0.68 | KMT2A (0.43) | — | |
| SCHEMBL23707218 | 0.67 | PDE10A (0.34) | PDE10A | |
| SCHEMBL23108890 | 0.67 | PDE10A (0.34) | PDE10A | |
| SCHEMBL25146924 | 0.67 | PDE10A (0.34) | PDE10A | |
| SCHEMBL6167461 | 0.67 | HRH2 (0.36) | PTGS1PTGS2HRH2HRH3 | |
| SCHEMBL30482992 | 0.67 | DGAT1 (0.41) | — | |
| SCHEMBL31046825 | 0.67 | DGAT1 (0.36) | PDE10A | |
| SCHEMBL293166 | 0.66 | MAPKAPK2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4029626-A | Polyurethane composition having easy-reentry property | COMMUNICATIONS TECHNOLOGY CORPORATION (US) | 1977-06-14 | — | — | US | disclosed |