Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 6/20 | 0.55 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.55 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.55 |
| ▸ | PTGIR | P43119 | 3/20 | 0.55 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | PTGFR | P43088 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SLCO2A1 | Q92959 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10938627 | 1.00 | PTGER4 (0.55) | PTGER4PTGER2PTGER3TBXA2RPTGIR | |
| SCHEMBL22489230 | 0.99 | TBXA2R (0.55) | PTGER4PTGER2PTGER3TBXA2RPTGIR | |
| SCHEMBL24479738 | 0.92 | TBXA2R (0.66) | PTGER4PTGER2PTGER3TBXA2RPTGIR | |
| SCHEMBL17421986 | 0.90 | PTGER4 (0.52) | PTGER4PTGER2PTGER3TBXA2RPTGIR | |
| SCHEMBL17421989 | 0.90 | PTGER4 (0.52) | PTGER4PTGER2PTGER3TBXA2RPTGIR | |
| SCHEMBL11093921 | 0.90 | PTGER4 (0.49) | PTGER4PTGER2PTGER3TBXA2RPTGIR | |
| SCHEMBL11093926 | 0.90 | PTGER4 (0.49) | PTGER4PTGER2PTGER3TBXA2RPTGIR | |
| SCHEMBL11546719 | 0.89 | TBXA2R (0.55) | PTGER4PTGER2PTGER3TBXA2RPTGIR | |
| SCHEMBL11728187 | 0.89 | TBXA2R (0.55) | PTGER4PTGER2PTGER3TBXA2RPTGIR | |
| SCHEMBL11450991 | 0.88 | PTGER4 (0.44) | PTGER4PTGER2PTGER3TBXA2RPTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017534-A | BRONCHODILATION, ANTISECRETORY | AMERICAN CYANAMID COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
| US-3932463-A | BRONCHODILATORS, GASTRIC ACID SECRETION INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1976-01-13 | — | — | US | disclosed |