Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.52 |
| ▸ | PTGFR | P43088 | 3/20 | 0.52 |
| ▸ | PTGIR | P43119 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SLCO2A1 | Q92959 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17421989 | 1.00 | PTGER4 (0.52) | PTGER4PTGER3PTGER2PTGER1TBXA2R | |
| SCHEMBL22489230 | 0.91 | TBXA2R (0.55) | PTGER4PTGER3PTGER2PTGER1TBXA2R | |
| SCHEMBL11757808 | 0.90 | PTGER4 (0.55) | PTGER4PTGER3PTGER2PTGER1TBXA2R | |
| SCHEMBL10938627 | 0.90 | PTGER4 (0.55) | PTGER4PTGER3PTGER2PTGER1TBXA2R | |
| SCHEMBL20740228 | 0.87 | PTGER4 (0.59) | PTGER4PTGER3PTGER2PTGER1TBXA2R | |
| SCHEMBL20740227 | 0.87 | PTGER4 (0.59) | PTGER4PTGER3PTGER2PTGER1TBXA2R | |
| SCHEMBL11546719 | 0.86 | TBXA2R (0.55) | PTGER4PTGER3PTGER2PTGER1TBXA2R | |
| SCHEMBL11728187 | 0.86 | TBXA2R (0.55) | PTGER4PTGER3PTGER2PTGER1TBXA2R | |
| SCHEMBL17421898 | 0.86 | PDE4D (0.57) | PTGER4PTGER3PTGER2PTGER1TBXA2R | |
| SCHEMBL17421896 | 0.86 | PDE4D (0.57) | PTGER4PTGER3PTGER2PTGER1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166918-B1 | METAL-CATALYZED ASYMMETRIC 1,4-CONJUGATE ADDITION OF VINYLBORON COMPOUNDS TO 2-SUBSTITUTED-4-OXY- CYCLOPENT-2-EN-1-ONES YIELDING PROSTAGLANDINS AND PROSTAGLANDIN ANALOGS | SCINOPHARM TAIWAN LTD (TW) | 2019-02-20 | — | — | EP | disclosed |
| US-9670234-B2 | Metal-catalyzed asymmetric 1,4-conjugate addition of vinylboron compounds to 2-substituted-4-oxy-cyclopent-2-en-1-ones yielding prostaglandins and prostaglandin analogs | SCINOPHARM TAIWAN, LTD. (TW) | 2017-06-06 | — | — | US | disclosed |
| US-20160009740-A1 | METAL-CATALYZED ASYMMETRIC 1,4-CONJUGATE ADDITION OF VINYLBORON COMPOUNDS TO 2-SUBSTITUTED-4-OXY-CYCLOPENT-2-EN-1-ONES YIELDING PROSTAGLANDINS AND PROSTAGLANDIN ANALOGS | SCINOPHARM TAIWAN, LTD. (TW) | 2016-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009740-A1 | METAL-CATALYZED ASYMMETRIC 1,4-CONJUGATE ADDITION OF VINYLBORON COMPOUNDS TO 2-SUBSTITUTED-4-OXY-CYCLOPENT-2-EN-1-ONES YIELDING PROSTAGLANDINS AND PROSTAGLANDIN ANALOGS | PTGIS, PTGER1, PTGS1 | PTGER4 8/4885PTGER3 12/4885PTGER2 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.