Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | VDR | P11473 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11878828 | 0.79 | ALDH1A1 (0.39) | ALDH1A1VDRLMNAMAPTRECQL | |
| SCHEMBL11878836 | 0.79 | ALDH1A1 (0.39) | ALDH1A1VDRLMNAMAPTRECQL | |
| SCHEMBL10808066 | 0.73 | ALDH1A1 (0.47) | ALDH1A1MIFVDRLMNAMAPT | |
| SCHEMBL9549291 | 0.73 | ALDH1A1 (0.52) | ALDH1A1MIFLMNAMAPTKDM4E | |
| SCHEMBL28172956 | 0.73 | CA12 (0.43) | ALDH1A1VDRLMNAMAPTMAPK1 | |
| SCHEMBL9142708 | 0.72 | ALDH1A1 (0.44) | ALDH1A1MIFVDRLMNAMAPT | |
| SCHEMBL10998010 | 0.72 | ALDH1A1 (0.85) | ALDH1A1MIFVDRCES1LMNA | |
| SCHEMBL15082846 | 0.72 | ALDH1A1 (0.85) | ALDH1A1MIFVDRCES1LMNA | |
| SCHEMBL241884 | 0.72 | CA1 (0.52) | ALDH1A1VDRLMNAHPGDKMT2A | |
| SCHEMBL3694647 | 0.71 | HPGD (0.60) | ALDH1A1VDRLMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4003915-A | ANTICONVULSANTS, PARKINSON*S DISEASE | HOFFMANN-LA ROCHE INC. (US) | 1977-01-18 | — | — | US | disclosed |