Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.62 |
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | TP53 | P04637 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.61 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.61 |
| ▸ | PLG | P00747 | 2/20 | 0.54 |
| ▸ | KLK1 | P06870 | 2/20 | 0.54 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.54 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.54 |
| ▸ | FADS1 | O60427 | 1/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11766334 | 0.90 | PLG (0.66) | NPC1RAB9AKMT2AMEN1TP53 | |
| SCHEMBL11762173 | 0.81 | NPC1 (0.69) | NPC1RAB9AKMT2AMEN1TP53 | |
| SCHEMBL17779250 | 0.80 | NPC1 (0.67) | NPC1RAB9AKMT2AMEN1TP53 | |
| SCHEMBL11763911 | 0.80 | MAPT (0.58) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL30307513 | 0.77 | RAB9A (1.00) | NPC1RAB9AKMT2AMEN1TP53 | |
| SCHEMBL27347841 | 0.77 | RAB9A (1.00) | NPC1RAB9AKMT2AMEN1TP53 | |
| SCHEMBL2743100 | 0.76 | NPC1 (1.00) | NPC1RAB9AKMT2AMEN1TP53 | |
| SCHEMBL29616891 | 0.76 | NPC1 (1.00) | NPC1RAB9AKMT2AMEN1TP53 | |
| SCHEMBL11761696 | 0.76 | PLG (0.67) | NPC1RAB9AKMT2AMEN1TP53 | |
| SCHEMBL6580139 | 0.75 | NPC1 (0.63) | NPC1RAB9AKMT2AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008274-A | ANTIFOULING | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JA) | 1977-02-15 | — | — | US | disclosed |