Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.58 |
| ▸ | EBP | Q15125 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.55 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11758728 | 0.86 | NPC1 (0.77) | NPC1RAB9AALDH1A1LMNAMAPK1 | |
| SCHEMBL9490019 | 0.83 | NPC1 (0.72) | NPC1RAB9AMAPK1TSHRMEN1 | |
| SCHEMBL11758823 | 0.83 | NPC1 (0.72) | NPC1RAB9AMAPK1TSHRMEN1 | |
| SCHEMBL11760321 | 0.82 | ALDH1A1 (0.64) | NPC1RAB9AALDH1A1ACHEMEN1 | |
| SCHEMBL11758017 | 0.81 | NPC1 (0.71) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL31285050 | 0.81 | NPC1 (0.65) | NPC1RAB9AALDH1A1MAPK1TSHR | |
| SCHEMBL31285555 | 0.81 | NPC1 (0.65) | NPC1RAB9AALDH1A1MAPK1TSHR | |
| SCHEMBL11756776 | 0.81 | NPC1 (0.97) | NPC1RAB9AALDH1A1LMNAMEN1 | |
| SCHEMBL10379918 | 0.81 | NPC1 (0.70) | NPC1RAB9ASIGMAR1ALDH1A1LMNA | |
| SCHEMBL19275417 | 0.80 | NPC1 (0.67) | NPC1RAB9AALDH1A1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4009208-A | N,N'-HEPTAMETHYLENEBIS(4-METHOXYBENZAMIDE) | STERLING DRUG INC. (US) | 1977-02-22 | — | — | US | disclosed |