Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 7/20 | 0.91 |
| ▸ | APEX1 | P27695 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.49 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CD40 | P25942 | 1/20 | 0.43 |
| ▸ | CD40LG | P29965 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11758959 | 1.00 | ENPP2 (0.91) | ENPP2APEX1CYP1A2SUMO2SUMO1 | |
| SCHEMBL11763856 | 0.94 | ENPP2 (0.96) | ENPP2APEX1CYP1A2SUMO2SUMO1 | |
| SCHEMBL11759867 | 0.92 | ENPP2 (0.82) | ENPP2APEX1CYP1A2SUMO2SUMO1 | |
| SCHEMBL11765373 | 0.92 | ENPP2 (0.82) | ENPP2APEX1CYP1A2SUMO2SUMO1 | |
| SCHEMBL11759923 | 0.91 | ENPP2 (0.82) | ENPP2APEX1CYP1A2SUMO2SUMO1 | |
| SCHEMBL10891071 | 0.90 | ENPP2 (0.85) | ENPP2APEX1CYP1A2SUMO2SUMO1 | |
| SCHEMBL11594349 | 0.90 | ENPP2 (0.85) | ENPP2APEX1CYP1A2SUMO2SUMO1 | |
| SCHEMBL29637807 | 0.90 | ENPP2 (0.85) | ENPP2APEX1CYP1A2SUMO2SUMO1 | |
| SCHEMBL30716918 | 0.90 | ENPP2 (0.85) | ENPP2APEX1CYP1A2SUMO2SUMO1 | |
| SCHEMBL10891093 | 0.90 | ENPP2 (0.85) | ENPP2APEX1CYP1A2SUMO2SUMO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008320-A | Amidophenyl-azo-naphthalenesulfonic complement inhibitors and method of use thereof | AMERICAN CYANAMID COMPANY (US) | 1977-02-15 | — | — | US | claimed |
| US-4049640-A | Substituted bisnaphthylazo diphenyl ureido complement inhibitors | AMERICAN CYANAMID COMPANY (US) | 1977-09-20 | — | — | US | disclosed |
| US-4008320-A | Amidophenyl-azo-naphthalenesulfonic complement inhibitors and method of use thereof | AMERICAN CYANAMID COMPANY (US) | 1977-02-15 | — | — | US | disclosed |