Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11759088 | 1.00 | NPC1 (0.59) | NPC1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL6550515 | 0.81 | KMT2A (0.63) | NPC1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL6550519 | 0.81 | KMT2A (0.63) | NPC1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL8660991 | 0.80 | KMT2A (0.61) | NPC1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL11800172 | 0.80 | MAPT (0.76) | NPC1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL27157136 | 0.78 | IDO1 (0.59) | NPC1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL131175 | 0.77 | MAPT (1.00) | NPC1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL574042 | 0.77 | MAPT (1.00) | NPC1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL29354111 | 0.77 | MAPT (1.00) | NPC1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL11754979 | 0.76 | ATIC (0.53) | KMT2AMEN1MAPTLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4050945-A | METALLIC COMPOUND REACTANT, CHELATING COMPOUND REACTANT, BINDER | SUZUKI YOSHIO | 1977-09-27 | — | — | US | disclosed |