Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | USP5 | P45974 | 1/20 | 0.49 |
| ▸ | GCGR | P47871 | 2/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11757497 | 0.89 | KMT2A (0.53) | KMT2AFFAR1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL11757895 | 0.85 | SRD5A2 (0.61) | KMT2AFFAR1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL7862861 | 0.83 | FFAR1 (0.51) | KMT2AFFAR1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL3746956 | 0.82 | SRD5A2 (0.64) | SMN1; SMN2RAB9ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7857464 | 0.80 | SMN1; SMN2 (0.72) | KMT2AFFAR1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL8532994 | 0.79 | SMN1; SMN2 (0.67) | KMT2AFFAR1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL11765494 | 0.79 | FFAR1 (0.53) | FFAR1SMN1; SMN2GCGRSLC1A3SLC1A2 | |
| SCHEMBL11759728 | 0.79 | RAB9A (0.47) | KMT2AFFAR1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL8688272 | 0.79 | HTT (0.62) | KMT2AFFAR1LMNASMN1; SMN2HIF1A | |
| SCHEMBL392858 | 0.78 | NR4A2 (0.65) | KMT2AFFAR1LMNASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4021479-A | ANTIPHLOGISTICS AND ANTIPROLIFERATIVES | BOEHRINGER INGELHEIM GMBH (DT) | 1977-05-03 | — | — | US | disclosed |