Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14808705 | 0.82 | ALDH1A1 (0.58) | GAAALDH1A1 | |
| SCHEMBL14808496 | 0.81 | GAA (0.53) | GAAALDH1A1KDM2BATMMAPT | |
| SCHEMBL27894145 | 0.78 | GAA (0.46) | GAAALDH1A1KDM2BATMRAB9A | |
| SCHEMBL14808331 | 0.78 | ALDH1A1 (0.69) | GAAALDH1A1CHRNA7 | |
| SCHEMBL14808505 | 0.77 | ALDH1A1 (0.56) | GAAALDH1A1ATM | |
| SCHEMBL14807964 | 0.75 | ALDH1A1 (0.70) | GAAALDH1A1KDM2BRAB9AMGLL | |
| SCHEMBL14808557 | 0.74 | ALDH1A1 (0.53) | GAAALDH1A1RAB9ACHRNA7MAPT | |
| SCHEMBL14821867 | 0.74 | ALDH1A1 (0.57) | GAAALDH1A1CHRNA7 | |
| SCHEMBL14808313 | 0.74 | TSHR (0.61) | GAAALDH1A1KDM2BMGLLHSD11B1 | |
| SCHEMBL14808621 | 0.73 | ALDH1A1 (0.67) | GAAALDH1A1KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4038402-A | METHOD OF EFFECTING ANTIHISTAMINIC, ANTISEROTONIN AND ANTIALLERGIC ACTIONS | KAMINKA MIKHAIL EMMANUILOVICH | 1977-07-26 | — | — | US | disclosed |