Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11765201 | 0.99 | SLC2A1 (0.56) | SLC2A1ADRB2ADRB1ADRB3KMT2A | |
| Hydrochloric Acid SCHEMBL11762600 | 0.84 | SLC2A1 (0.58) | SLC2A1ADRB2ADRB1ADRB3KMT2A | |
| Cloranolol SCHEMBL80493 | 0.82 | SLC2A1 (0.62) | SLC2A1ADRB2ADRB1ADRB3KMT2A | |
| Cloranolol SCHEMBL80494 | 0.82 | SLC2A1 (0.62) | SLC2A1ADRB2ADRB1ADRB3KMT2A | |
| Hydrochloric Acid SCHEMBL11760705 | 0.81 | MAPT (0.67) | ADRB2ADRB1ADRB3KMT2AMAPT | |
| Cloranolol SCHEMBL1230787 | 0.81 | KMT2A (0.63) | SLC2A1ADRB2ADRB1ADRB3KMT2A | |
| Cloranolol SCHEMBL1230788 | 0.81 | KMT2A (0.63) | SLC2A1ADRB2ADRB1ADRB3KMT2A | |
| Cloranolol SCHEMBL1649063 | 0.80 | SLC2A1 (0.59) | SLC2A1ADRB2ADRB1ADRB3KMT2A | |
| SCHEMBL11872099 | 0.79 | HTR1A (0.70) | SLC2A1ADRB2ADRB1ADRB3KMT2A | |
| Hydrochloric Acid SCHEMBL11758427 | 0.78 | HTR1A (0.68) | SLC2A1ADRB2ADRB1ADRB3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4039685-A | 1-PHENOXY-2-HYDROXY-3-TERT.-BUTYLAMINO PROPANE ANTIARRHYTHMIC COMPOUNDS | BOEHRINGER INGELHEIM GMBH (DT) | 1977-08-02 | — | — | US | disclosed |
| US-3961071-A | CARDIOVASCULAR DISORDERS, 1-PHENOXY-2-HYDROXY-3-TERT-BUTYLAMINO PROPANES | BOEHRINGER INGELHEIM GMBH (DT) | 1976-06-01 | — | — | US | disclosed |