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SCHEMBL11760447

SCHEMBL11760447

O=C1NC(O)CCN1[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ HPRT1 P00492 1/20 0.53
▸ FBP1 P09467 2/20 0.51
▸ UMPS P11172 5/20 0.49
▸ DNPH1 O43598 1/20 0.49
▸ P2RY2 P41231 2/20 0.46
▸ LDHA P00338 1/20 0.46
▸ P2RY6 Q15077 1/20 0.46
▸ ATIC P31939 2/20 0.45
▸ GART P22102 1/20 0.45
▸ CDA P32320 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11755974 1.00 HPRT1 (0.53) HPRT1FBP1UMPSDNPH1P2RY2
SCHEMBL11753918 0.91 P2RY2 (0.52) P2RY2P2RY6
SCHEMBL11756652 0.89 P2RY2 (0.55) P2RY2P2RY6
SCHEMBL11758791 0.81 CDA (0.62) HPRT1FBP1UMPSDNPH1P2RY2
SCHEMBL11755358 0.81 CDA (0.62) HPRT1FBP1UMPSDNPH1P2RY2
SCHEMBL11759377 0.81 CDA (0.49) CDA
SCHEMBL11178912 0.80 HPRT1 (0.53) HPRT1FBP1UMPSDNPH1P2RY2
Tetrahydrouridine SCHEMBL11761038 0.80 CDA (0.66) CDA
Tetrahydrouridine SCHEMBL587704 0.80 CDA (0.66) CDA
Tetrahydrouridine SCHEMBL11759489 0.80 CDA (0.66) CDA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4017606-A CYTOSINE ARABINOSIDE AND HYDROGENATED PYRIMIDINE NUCLEOSIDES THE UPJOHN COMPANY (US) 1977-04-12 — — US disclosed