Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fexinidazole Sulfone SCHEMBL11756026 | 0.89 | LMNA (0.54) | LMNACYP2C19IDO1SMN1; SMN2NPC1 | |
| SCHEMBL11757498 | 0.87 | LMNA (0.48) | LMNACYP2C19SMN1; SMN2NPC1KMT2A | |
| SCHEMBL11756711 | 0.86 | LMNA (0.41) | LMNASMN1; SMN2ALDH1A1CA2CA9 | |
| SCHEMBL11755910 | 0.84 | LMNA (0.58) | LMNACYP2C19IDO1KMT2AALDH1A1 | |
| SCHEMBL11727784 | 0.83 | LMNA (0.56) | LMNACYP2C19IDO1NPC1KMT2A | |
| SCHEMBL11635148 | 0.83 | LMNA (0.60) | LMNACYP2C19IDO1NPC1KMT2A | |
| SCHEMBL11641060 | 0.83 | LMNA (0.59) | LMNACYP2C19NPC1KMT2AALDH1A1 | |
| SCHEMBL11756631 | 0.82 | LMNA (0.53) | LMNACYP2C19IDO1NPC1KMT2A | |
| SCHEMBL15752483 | 0.82 | LMNA (0.59) | LMNACYP2C19IDO1NPC1KMT2A | |
| SCHEMBL11731771 | 0.81 | LMNA (0.55) | LMNACYP2C19IDO1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4031232-A | 1-Alkyl-2-(phenoxymethyl)-5-nitro-imidazoles and process for their manufacture | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-06-21 | — | — | US | claimed |
| US-4031232-A | 1-Alkyl-2-(phenoxymethyl)-5-nitro-imidazoles and process for their manufacture | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-06-21 | — | — | US | disclosed |