Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.41 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11761398 | 1.00 | MCL1 (0.55) | MCL1NPC1RAB9APOLBPKM | |
| SCHEMBL4630811 | 0.82 | MCL1 (0.52) | MCL1NPC1RAB9APOLBPKM | |
| SCHEMBL4630806 | 0.82 | MCL1 (0.52) | MCL1NPC1RAB9APOLBPKM | |
| SCHEMBL9075825 | 0.80 | MCL1 (0.50) | MCL1NPC1RAB9APOLBPKM | |
| SCHEMBL10187523 | 0.80 | MCL1 (0.50) | MCL1NPC1RAB9APOLBPKM | |
| SCHEMBL14604980 | 0.80 | MCL1 (0.50) | MCL1NPC1RAB9APOLBPKM | |
| SCHEMBL18192045 | 0.80 | MCL1 (0.50) | MCL1NPC1RAB9APOLBPKM | |
| SCHEMBL14667451 | 0.79 | MCL1 (0.50) | MCL1NPC1RAB9APOLBPKM | |
| SCHEMBL7109240 | 0.77 | MCL1 (0.47) | MCL1NPC1RAB9APOLBPKM | |
| SCHEMBL11764470 | 0.77 | MCL1 (0.51) | MCL1NPC1RAB9APOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4052553-A | BACTERICIDE, ANTIMALARIAL | BURROUGHS WELLCOME CO. (US) | 1977-10-04 | — | — | US | disclosed |