SCHEMBL18192045

SCHEMBL18192045

CCC(C#N)=Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.50
ALDH1A1 P00352 5/20 0.44
POLB P06746 3/20 0.44
RAB9A P51151 3/20 0.42
NPC1 O15118 2/20 0.42
PKM P14618 2/20 0.42
KDM1A O60341 1/20 0.42
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
MAPT P10636 3/20 0.41
LMNA P02545 3/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PLIN1 O60240 1/20 0.41
PLIN5 Q00G26 1/20 0.41
ABHD5 Q8WTS1 1/20 0.41
KDM4E B2RXH2 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
HPGD P15428 1/20 0.40
MAPK1 P28482 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14604980 1.00 MCL1 (0.50) MCL1ALDH1A1POLBRAB9ANPC1
SCHEMBL10187523 1.00 MCL1 (0.50) MCL1ALDH1A1POLBRAB9ANPC1
SCHEMBL15521648 0.86 ALDH1A1 (0.48) ALDH1A1POLBRAB9ANPC1KMT2A
SCHEMBL8402113 0.85 LTA4H (0.43) ALDH1A1RAB9ANPC1KMT2AMEN1
SCHEMBL28645928 0.85 MCL1 (0.47) MCL1ALDH1A1POLBRAB9ANPC1
SCHEMBL14616300 0.82 KMT2A (0.57) ALDH1A1POLBPKMKMT2AMEN1
SCHEMBL20143067 0.82 LMNA (0.49) MCL1ALDH1A1POLBRAB9ANPC1
SCHEMBL4630811 0.82 MCL1 (0.52) MCL1ALDH1A1POLBRAB9ANPC1
SCHEMBL4630806 0.82 MCL1 (0.52) MCL1ALDH1A1POLBRAB9ANPC1
SCHEMBL28752642 0.80 LMNA (0.55) MCL1ALDH1A1POLBRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3315535-B1 METHOD OF PRODUCTION OF CONJUGATED DIENE RUBBER ZEON CORP (JP) 2019-11-13 EP disclosed
US-20190292289-A1 METHOD FOR PRODUCING FOR CONJUGATED-DIENE-BASED RUBBER ZEON CORPORATION (JP) 2019-09-26 US disclosed
EP-3543278-A1 METHOD FOR PRODUCING CONJUGATED-DIENE-BASED RUBBER Zeon Corporation (JP) 2019-09-25 EP disclosed
US-10266613-B2 Conjugated diene polymer and method of production of conjugated diene polymer ZEON CORPORATION (JP) 2019-04-23 US disclosed
EP-3088423-B1 CONJUGATED DIENE BASED POLYMER AND PROCESS FOR MANUFACTURING CONJUGATED DIENE BASED POLYMER ZEON CORP (JP) 2019-01-16 EP disclosed
US-20180298121-A1 CONJUGATED DIENE POLYMER AND METHOD OF PRODUCTION OF CONJUGATED DIENE POLYMER ZEON CORPORATION (JP) 2018-10-18 US disclosed
US-20180170103-A1 METHOD OF PRODUCTION OF CONJUGATED DIENE RUBBER ZEON CORPORATION (JP) 2018-06-21 US disclosed
EP-3315535-A1 METHOD OF PRODUCTION OF CONJUGATED DIENE RUBBER Zeon Corporation (JP) 2018-05-02 EP disclosed
EP-3309181-A1 CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCTION CONJUGATED DIENE POLYMER Zeon Corporation (JP) 2018-04-18 EP disclosed
CN-107709412-A The manufacture method of conjugated diene rubber 日本瑞翁株式会社 2018-02-16 CN disclosed
CN-107614537-A Conjugated diene polymer and method for producing conjugated diene polymer 日本瑞翁株式会社 2018-01-19 CN disclosed
US-20160326274-A1 CONJUGATED DIENE POLYMER AND METHOD OF PRODUCTION OF CONJUGATED DIENE POLYMER ZEON CORPORATION (JP) 2016-11-10 US disclosed
EP-3088423-A1 CONJUGATED DIENE BASED POLYMER AND PROCESS FOR MANUFACTURING CONJUGATED DIENE BASED POLYMER Zeon Corporation (JP) 2016-11-02 EP disclosed
CN-105849134-A Conjugated diene based polymer and process for manufacturing conjugated diene based polymer 日本瑞翁株式会社 2016-08-10 CN disclosed