Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.55 |
| ▸ | CTSV | O60911 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | DDX3X | O00571 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11765011 | 0.91 | ABCG2 (0.55) | ABCG2MAPTALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL11763825 | 0.87 | AKR1C3 (0.52) | ABCG2MAPTALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL11762199 | 0.86 | AKR1C3 (0.58) | ABCG2MAPTALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL11760920 | 0.86 | ALDH1A1 (0.62) | MAPTALDH1A1AKR1C3AKR1C2CTSV | |
| SCHEMBL11767831 | 0.86 | ABCG2 (0.48) | ABCG2MAPTALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL11764491 | 0.85 | MAPT (0.52) | ABCG2MAPTALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL11760951 | 0.85 | RXFP1 (0.51) | ABCG2MAPTALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL11765507 | 0.84 | POLB (0.56) | ABCG2MAPTALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL29779874 | 0.83 | AKR1C3 (0.67) | MAPTALDH1A1AKR1C3AKR1C2CTSV | |
| SCHEMBL11763360 | 0.82 | SMN1; SMN2 (0.57) | ABCG2MAPTALDH1A1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4016166-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, CNS DEPRESSANTS | HISAMITSU PHARMACEUTICAL CO., INC. (JA) | 1977-04-05 | — | — | US | disclosed |