Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11762419 | 0.90 | RAB9A (0.53) | KDM4EALDH1A1RAB9ADRD2PTGES | |
| SCHEMBL11762851 | 0.90 | KDM4E (0.57) | KDM4EALDH1A1RAB9ADRD2PTGES | |
| SCHEMBL11762024 | 0.90 | RAB9A (0.56) | KDM4EALDH1A1RAB9ADRD2PTGES | |
| SCHEMBL11764061 | 0.90 | KDM4E (0.50) | KDM4EALDH1A1RAB9ADRD2PTGES | |
| SCHEMBL11408123 | 0.90 | KDM4E (0.64) | KDM4EALDH1A1RAB9ADRD2PTGES | |
| SCHEMBL11765344 | 0.88 | RAB9A (0.57) | KDM4EALDH1A1RAB9ADRD2PTGES | |
| SCHEMBL11762985 | 0.88 | RAB9A (0.81) | KDM4EALDH1A1RAB9AHTTMAPT | |
| SCHEMBL11762318 | 0.87 | RAB9A (0.47) | KDM4EALDH1A1RAB9ADRD2PTGES | |
| SCHEMBL11763741 | 0.87 | RAB9A (0.47) | KDM4EALDH1A1RAB9ADRD2LMNA | |
| SCHEMBL11764927 | 0.86 | RAB9A (0.52) | KDM4EALDH1A1RAB9ADRD2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042706-A | Novel anti-inflammatory pyrazole derivatives and preparation thereof | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-08-16 | — | — | US | claimed |
| US-4042706-A | Novel anti-inflammatory pyrazole derivatives and preparation thereof | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-08-16 | — | — | US | disclosed |