Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.58 |
| ▸ | CTSS | P25774 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11764270 | 1.00 | CTSK (0.58) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL18775048 | 0.90 | CTSK (0.60) | CTSKCTSSCTSLCTSBS1PR4 | |
| SCHEMBL25634730 | 0.90 | CTSK (0.60) | CTSKCTSSCTSLCTSBS1PR4 | |
| SCHEMBL14092277 | 0.87 | CTSK (0.58) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL18791072 | 0.85 | CTSK (0.62) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL18775040 | 0.85 | CTSK (0.62) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL11761725 | 0.83 | CTSK (0.62) | CTSKCTSSCTSLCTSB | |
| SCHEMBL11761731 | 0.83 | CTSK (0.62) | CTSKCTSSCTSLCTSB | |
| SCHEMBL31634257 | 0.83 | CTSK (0.60) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL31634270 | 0.83 | CTSK (0.60) | CTSKCTSSCTSLCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064236-A | Peptide carbazates and pharmaceutical composition | MERCK & CO., INC. (US) | 1977-12-20 | — | — | US | disclosed |