Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11783073 | 1.00 | HPGD (0.43) | HPGDMAPTACACBLMNAMEN1 | |
| SCHEMBL11138250 | 0.87 | MAPT (0.46) | HPGDMAPTLMNAMEN1KMT2A | |
| SCHEMBL11138252 | 0.87 | MAPT (0.46) | HPGDMAPTLMNAMEN1KMT2A | |
| SCHEMBL1553411 | 0.86 | ALDH1A1 (0.42) | HPGDMAPTLMNAMEN1KMT2A | |
| SCHEMBL1553412 | 0.86 | ALDH1A1 (0.42) | HPGDMAPTLMNAMEN1KMT2A | |
| SCHEMBL1554070 | 0.83 | DHODH (0.44) | HPGDMAPTLMNAMEN1KMT2A | |
| SCHEMBL1554071 | 0.83 | DHODH (0.44) | HPGDMAPTLMNAMEN1KMT2A | |
| SCHEMBL11668967 | 0.82 | PTGS1 (0.45) | HPGDACACBLMNAMEN1KMT2A | |
| SCHEMBL11639636 | 0.82 | PTGS1 (0.45) | HPGDACACBLMNAMEN1KMT2A | |
| SCHEMBL1554675 | 0.81 | MAPT (0.47) | HPGDMAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-52118445-A | — | — | None | — | — | JP | disclosed |
| JP-52062237-A | — | — | None | — | — | JP | disclosed |
| JP-S52118445-A | 2-CYANO-3-METHYL-3-(4-ISOBUTYLPHENYL)ACRYLIC ACID DERIVATIVES AND MET HOD OF PREPARING THE SAME | GRELAN PHARMACEUT CO LTD | 1977-10-04 | — | — | JP | disclosed |
| JP-S5262237-A | PROCESS FOR PREPARATION OF ALPHA-SUBSTITUTED PHENYLALKANE CARBOXYLIC A CID | ONO PHARMACEUT CO LTD | 1977-05-23 | — | — | JP | disclosed |