Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11365470 | 0.98 | TSHR (0.35) | TSHRSMN1; SMN2OPRM1FFAR1FFAR4 | |
| SCHEMBL23142415 | 0.98 | TSHR (0.35) | TSHRSMN1; SMN2OPRM1FFAR1FFAR4 | |
| SCHEMBL11599041 | 0.98 | TSHR (0.35) | TSHRSMN1; SMN2OPRM1FFAR1FFAR4 | |
| SCHEMBL8945258 | 0.94 | TSHR (0.39) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL3687450 | 0.86 | FFAR1 (0.37) | TSHRSMN1; SMN2FFAR1FFAR4PTGS1 | |
| SCHEMBL9580842 | 0.85 | — | — | |
| SCHEMBL9244360 | 0.85 | FFAR1 (0.46) | TSHRFFAR1FFAR4LMNAPTGS1 | |
| SCHEMBL28246293 | 0.85 | FFAR1 (0.46) | TSHRFFAR1FFAR4LMNAPTGS1 | |
| SCHEMBL9724790 | 0.80 | TSHR (0.42) | TSHRSMN1; SMN2OPRM1LMNAALDH1A1 | |
| SCHEMBL9308196 | 0.80 | TSHR (0.39) | TSHRSMN1; SMN2FFAR1FFAR4PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4028431-A | ETHYLENE-HEXAFLUOROPROPYLENE POLYMER, SILICONE RUBBERS, AND VINYLIDENE FLUORIDE COPOLYMER | DAIKIN KOGYO CO., LTD. (JA) | 1977-06-07 | — | — | US | disclosed |