Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11765258 | 0.94 | TSHR (0.33) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL23142415 | 0.92 | TSHR (0.35) | TSHRSMN1; SMN2DNM1 | |
| SCHEMBL11599041 | 0.92 | TSHR (0.35) | TSHRSMN1; SMN2DNM1 | |
| SCHEMBL11365470 | 0.92 | TSHR (0.35) | TSHRSMN1; SMN2DNM1 | |
| SCHEMBL9580842 | 0.87 | — | — | |
| SCHEMBL9308196 | 0.86 | TSHR (0.39) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL18676850 | 0.82 | TSHR (0.38) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL3638966 | 0.80 | TSHR (0.43) | TSHRSMN1; SMN2ALDH1A1DNM1 | |
| SCHEMBL3687450 | 0.80 | FFAR1 (0.37) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL9015918 | 0.79 | TSHR (0.50) | TSHRSMN1; SMN2ALDH1A1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5549907-A | Ionomeric suture and its method of manufacture | UNITED STATES SURGICAL CORPORATION (US) | 1996-08-27 | — | — | US | disclosed |
| EP-0588088-A1 | Filament fabricated from a blend of ionomer resin and nonionic thermoplastic resin and melt extrusion process for fabricating the filament | United States Surgical Corporation (US) | 1994-03-23 | — | — | EP | disclosed |
| EP-0588302-A1 | Ionomeric suture its manufacture and method of use | United States Surgical Corporation (US) | 1994-03-23 | — | — | EP | disclosed |
| US-5284489-A | Sutures; surgical mesh | UNITED STATES SURGICAL CORPORATION (US) | 1994-02-08 | — | — | US | disclosed |
| US-5006267-A | Biocidal fluid filters | THE DOW CHEMICAL COMPANY (US) | 1991-04-09 | — | — | US | disclosed |