SCHEMBL11765331

SCHEMBL11765331

CCCC1=C(CCCCCCC(=O)OC)C(=O)CC1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
ALDH1A1 P00352 2/20 0.39
POLB P06746 2/20 0.39
RECQL P46063 1/20 0.39
HIF1A Q16665 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TSHR P16473 2/20 0.39
HPGD P15428 1/20 0.38
PTGER2 P43116 3/20 0.37
EPHX2 P34913 2/20 0.37
DGKA P23743 1/20 0.37
PTGER4 P35408 1/20 0.36
PTGER3 P43115 1/20 0.36
SCD O00767 1/20 0.36
KMT2A Q03164 1/20 0.35
POLA1 P09884 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
KAT2B Q92831 1/20 0.34
PRKCA P17252 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11765129 0.93 SCD (0.45) LMNAALDH1A1POLBRECQLHIF1A
SCHEMBL11763111 0.93 SCD (0.42) LMNAALDH1A1POLBRECQLHIF1A
SCHEMBL11766118 0.93 SCD (0.45) LMNAALDH1A1POLBRECQLHIF1A
SCHEMBL11762428 0.93 SCD (0.45) LMNAALDH1A1POLBRECQLHIF1A
SCHEMBL11760628 0.93 SCD (0.45) LMNAALDH1A1POLBRECQLHIF1A
SCHEMBL11766551 0.90 TSHR (0.40) LMNAALDH1A1POLBRECQLHIF1A
SCHEMBL11766230 0.81 TSHR (0.42) LMNAALDH1A1POLBRECQLHIF1A
SCHEMBL9323832 0.81 TSHR (0.42) LMNAALDH1A1POLBRECQLHIF1A
SCHEMBL2142693 0.79 ALDH1A1 (0.38) LMNAALDH1A1POLBRECQLHIF1A
SCHEMBL10483614 0.79 TSHR (0.41) LMNAALDH1A1POLBRECQLHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4039563-A Process for preparing cyclopent-2-en-1-one derivatives TEIJIN LIMITED (JA) 1977-08-02 US disclosed