Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPY2R | P49146 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11203981 | 0.89 | ALDH1A1 (0.40) | MAPK1RECQLALDH1A1MAPTMEN1 | |
| SCHEMBL11203252 | 0.85 | GAA (0.38) | MAPK1RECQLALDH1A1MAPTMEN1 | |
| SCHEMBL9350181 | 0.81 | ADORA2A (0.43) | MAPK1RECQLALDH1A1MAPTMEN1 | |
| SCHEMBL11716067 | 0.70 | MAPK8 (0.42) | MAPK1RECQLALDH1A1MAPTMEN1 | |
| SCHEMBL11610490 | 0.70 | MAPK8 (0.35) | MAPK1RECQLALDH1A1MAPTMEN1 | |
| SCHEMBL11608450 | 0.70 | KDM4E (0.49) | MAPK1RECQLALDH1A1MAPTMEN1 | |
| SCHEMBL164493 | 0.70 | — | — | |
| SCHEMBL11765884 | 0.69 | ALDH1A1 (0.33) | MAPK1RECQLALDH1A1 | |
| SCHEMBL9013559 | 0.69 | ALDH1A1 (0.40) | RECQLALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11750122 | 0.69 | ALDH1A1 (0.50) | MAPK1ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4032322-A | ISOTHIAZOLYLFORMAMIDINE DERIVATIVES AS HERBICIDES | GIBBONS LOREN KENNETH | 1977-06-28 | — | — | US | disclosed |