Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925736 | 0.84 | TSHR (0.33) | TSHRHPGDCYP2C19MAPTALOX12 | |
| SCHEMBL8925749 | 0.84 | TSHR (0.33) | TSHRHPGDCYP2C19MAPTALOX12 | |
| SCHEMBL29087008 | 0.80 | ALDH1A1 (0.35) | TSHRHPGDNPSR1ALDH1A1 | |
| SCHEMBL6652850 | 0.77 | FFAR3 (0.38) | TSHRALDH1A1 | |
| SCHEMBL8741987 | 0.69 | EGLN1 (0.38) | TSHRMAPTNPSR1ALDH1A1 | |
| SCHEMBL6647598 | 0.68 | EGLN1 (0.37) | TSHRHPGDCYP2C19MAPTALOX12 | |
| SCHEMBL20970611 | 0.68 | TSHR (0.47) | TSHRHPGDCYP2C19MAPTALOX12 | |
| SCHEMBL6466345 | 0.67 | TSHR (0.33) | TSHRHPGDCYP2C19MAPTALOX12 | |
| SCHEMBL11150867 | 0.67 | — | — | |
| Methoxyacetic Acid SCHEMBL48842 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4026826-A | ALKOXYSILANES | JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) | 1977-05-31 | — | — | US | disclosed |