Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PREP | P48147 | 3/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11761514 | 0.94 | L3MBTL1 (0.46) | TSHRL3MBTL1KDM4ELMNAPREP | |
| SCHEMBL11765435 | 0.93 | NPSR1 (0.51) | TSHRL3MBTL1KDM4ELMNAPREP | |
| Hydrochloric Acid SCHEMBL11765503 | 0.92 | NPSR1 (0.50) | TSHRL3MBTL1KDM4ELMNAPREP | |
| SCHEMBL4158485 | 0.86 | TSHR (0.53) | TSHRL3MBTL1KDM4ELMNAPREP | |
| SCHEMBL14893288 | 0.82 | TSHR (0.64) | TSHRL3MBTL1KDM4ELMNAPREP | |
| SCHEMBL847403 | 0.82 | TSHR (0.64) | TSHRL3MBTL1KDM4ELMNAPREP | |
| SCHEMBL11764870 | 0.82 | NPSR1 (0.54) | KDM4ELMNAPREPACE2NPSR1 | |
| SCHEMBL11764878 | 0.82 | NPSR1 (0.54) | KDM4ELMNAPREPACE2NPSR1 | |
| SCHEMBL11764886 | 0.82 | NPSR1 (0.54) | KDM4ELMNAPREPACE2NPSR1 | |
| SCHEMBL11764245 | 0.81 | NPSR1 (0.53) | KDM4ELMNAPREPACE2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4022792-A | ANALGESICS | STERLING DRUG INC. (US) | 1977-05-10 | — | — | US | disclosed |
| US-3976653-A | ANALGESIC ANTAGONIST | STERLING DRUG INC. (US) | 1976-08-24 | — | — | US | disclosed |