Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL511319 | 0.95 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL19125483 | 0.94 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL11765093 | 0.91 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL11766140 | 0.90 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL11765255 | 0.89 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL124764 | 0.89 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL611483 | 0.87 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL28715888 | 0.87 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL11767225 | 0.86 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL844976 | 0.86 | SMN1; SMN2 (0.71) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4026826-A | ALKOXYSILANES | JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) | 1977-05-31 | — | — | US | disclosed |