Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11766007 | 1.00 | TDP1 (0.42) | TDP1ALDH1A1LMNACYP3A4HCAR2 | |
| SCHEMBL11765328 | 0.92 | ALDH1A1 (0.47) | TDP1ALDH1A1LMNACYP3A4HCAR2 | |
| SCHEMBL11765325 | 0.92 | ALDH1A1 (0.47) | TDP1ALDH1A1LMNACYP3A4HCAR2 | |
| SCHEMBL11762172 | 0.90 | TDP1 (0.54) | TDP1ALDH1A1LMNACYP3A4HCAR2 | |
| SCHEMBL11762177 | 0.90 | TDP1 (0.54) | TDP1ALDH1A1LMNACYP3A4HCAR2 | |
| SCHEMBL11866010 | 0.87 | TDP1 (0.43) | TDP1ALDH1A1LMNACYP3A4TSHR | |
| SCHEMBL11866019 | 0.87 | TDP1 (0.43) | TDP1ALDH1A1LMNACYP3A4TSHR | |
| SCHEMBL11867348 | 0.86 | TDP1 (0.42) | TDP1ALDH1A1LMNACYP3A4 | |
| SCHEMBL11868912 | 0.86 | TDP1 (0.45) | TDP1ALDH1A1LMNACYP3A4 | |
| SCHEMBL11867352 | 0.86 | TDP1 (0.42) | TDP1ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4021461-A | INSECTICIDES | ZOECON CORPORATION (US) | 1977-05-03 | — | — | US | disclosed |