Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11767328 | 0.91 | KDM1A (0.41) | HTR2AHTR2CHRH1HTR2BSIGMAR1 | |
| SCHEMBL4352504 | 0.76 | OPRL1 (0.68) | OPRM1OPRL1OPRK1 | |
| SCHEMBL467357 | 0.74 | OPRL1 (0.58) | SIGMAR1OPRM1OPRL1OPRK1SMN1; SMN2 | |
| SCHEMBL317531 | 0.74 | OPRL1 (0.47) | OPRM1OPRL1OPRK1 | |
| SCHEMBL11765120 | 0.74 | KDM4A (0.48) | SIGMAR1OPRM1OPRL1OPRK1MAPK1 | |
| SCHEMBL2019808 | 0.73 | MAPK1 (0.46) | OPRM1MAPK1SMN1; SMN2DRD4 | |
| SCHEMBL9586038 | 0.71 | MAPK1 (0.36) | OPRM1OPRL1MAPK1SMN1; SMN2TACR1 | |
| SCHEMBL11572399 | 0.71 | OPRL1 (0.52) | OPRM1OPRL1MAPK1SMN1; SMN2MAOB | |
| SCHEMBL11763463 | 0.70 | MAPK1 (0.44) | OPRM1OPRL1MAPK1SMN1; SMN2TACR1 | |
| SCHEMBL4354596 | 0.70 | SLC6A4 (0.65) | OPRM1OPRL1TACR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053637-A | ANTIDEPRESSANTS | ASTRA LAKEMEDAL AKTIEBOLAG (SW) | 1977-10-11 | — | — | US | disclosed |