Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | SNCA | P37840 | 2/20 | 0.51 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11767686 | 1.00 | THRB (0.52) | THRBSNCAMGLLKMT2AHDAC2 | |
| SCHEMBL11765937 | 0.93 | SNCA (0.52) | THRBSNCAMGLLKMT2AHDAC2 | |
| SCHEMBL11765941 | 0.93 | SNCA (0.52) | THRBSNCAMGLLKMT2AHDAC2 | |
| SCHEMBL11764696 | 0.91 | THRB (0.55) | THRBSNCAMGLLKMT2AALDH1A1 | |
| SCHEMBL11764699 | 0.91 | THRB (0.55) | THRBSNCAMGLLKMT2AALDH1A1 | |
| SCHEMBL11761767 | 0.90 | TSHR (0.54) | THRBSNCAMGLLALDH1A1RAB9A | |
| SCHEMBL11762130 | 0.90 | TSHR (0.54) | THRBSNCAMGLLALDH1A1RAB9A | |
| SCHEMBL11611649 | 0.90 | TSHR (0.54) | THRBSNCAMGLLALDH1A1RAB9A | |
| SCHEMBL11611652 | 0.90 | TSHR (0.54) | THRBSNCAMGLLALDH1A1RAB9A | |
| SCHEMBL11761761 | 0.90 | TSHR (0.54) | THRBSNCAMGLLALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061587-A | Liquid crystalline cinnamic acid esters | HOFFMANN-LA ROCHE INC. (US) | 1977-12-06 | — | — | US | disclosed |