Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL473080 | 0.96 | ALDH1A1 (0.63) | ALDH1A1TSHRTDP1MEN1LMNA | |
| SCHEMBL7638 | 0.96 | ALDH1A1 (0.63) | ALDH1A1TSHRTDP1MEN1LMNA | |
| SCHEMBL29405187 | 0.96 | ALDH1A1 (0.63) | ALDH1A1TSHRTDP1MEN1LMNA | |
| SCHEMBL8719955 | 0.93 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1MEN1LMNA | |
| SCHEMBL11016199 | 0.93 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1MEN1LMNA | |
| SCHEMBL9562250 | 0.93 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1MEN1LMNA | |
| Ethylene SCHEMBL7946796 | 0.93 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1MEN1LMNA | |
| Water SCHEMBL20379011 | 0.93 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1MEN1LMNA | |
| SCHEMBL22496001 | 0.93 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1MEN1LMNA | |
| Charcoal, Activated SCHEMBL6411785 | 0.93 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2063872-B1 | CONTROLLED RELEASE ORAL DOSAGE FORMULATIONS COMPRISING A CORE AND ONE OR MORE BARRIER LAYERS | JAGOTEC AG (CH) | 2015-05-06 | — | — | EP | claimed |
| US-20110028480-A1 | ORODISPERSABLE FORMULATIONS OF PHOSPHODIESTERASE-5 (PDE-5) INHIBITORS | OCEAN 1 806, LLC (US) | 2011-02-03 | — | — | US | claimed |
| WO-2009123626-A1 | ORODISPERSABLE FORMULATIONS OF PHOSPHODIESTERASE-5 (PDE-5) INHIBITORS | OCEAN 1 806, LLC (US) | 2009-10-08 | — | — | WO | claimed |
| EP-1019029-B1 | MONOLITHIC SYSTEM CONTAINING ONE OR MORE DRUGS, CONSISTING OF THREE LAYERS WITH DIFFERENT RELEASE MECHANISMS | CHIESI FARMA SPA (IT) | 2003-09-03 | — | — | EP | claimed |
| EP-4279075-B1 | A PHARMACEUTICAL COMPOSITION COMPRISING ELAGOLIX | ZAKL FARMACEUTYCZNE POLPHARMA S A (PL) | 2024-07-10 | — | — | EP | disclosed |
| EP-4279075-A1 | A PHARMACEUTICAL COMPOSITION COMPRISING ELAGOLIX | Zaklady Farmaceutyczne Polpharma S.A. (PL) | 2023-11-22 | — | — | EP | disclosed |
| US-9387190-B2 | Sustained release of topical anesthetics | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2016-07-12 | — | — | US | disclosed |
| US-20150297550-A1 | SUSTAINED RELEASE OF TOPICAL ANESTHETICS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2015-10-22 | — | — | US | disclosed |
| EP-2914258-A1 | SUSTAINED RELEASE OF TOPICAL ANESTHETICS | University Of Kentucky Research Foundation (US) | 2015-09-09 | — | — | EP | disclosed |
| US-8771716-B2 | Modified release analgesic suspensions | MCNEIL-PPC, INC. (US) | 2014-07-08 | — | — | US | disclosed |
| EP-2091515-B1 | MODIFIED RELEASE ANALGESIC SUSPENSIONS | MCNEIL PPC INC (US) | 2014-06-04 | — | — | EP | disclosed |
| WO-2014071203-A1 | SUSTAINED RELEASE OF TOPICAL ANESTHETICS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2014-05-08 | — | — | WO | disclosed |
| US-20130142846-A1 | Modified Release Analgesic Suspensions | MCNEIL-PPC, INC (US) | 2013-06-06 | — | — | US | disclosed |
| US-8394415-B2 | Liquid suspensions of a non-steroidal antiinflammatory agent (ibuprofen) and a decongestant (phenylephrine) having a protective enteric coating of a divinylbenzene-styrene or divinylbenzene-methacrylic acid copolymer; increased effective time between dosages | MCNEIL-PPC, INC (US) | 2013-03-12 | — | — | US | disclosed |
| US-20110028480-A1 | ORODISPERSABLE FORMULATIONS OF PHOSPHODIESTERASE-5 (PDE-5) INHIBITORS | OCEAN 1 806, LLC (US) | 2011-02-03 | — | — | US | disclosed |
| WO-2009123626-A1 | ORODISPERSABLE FORMULATIONS OF PHOSPHODIESTERASE-5 (PDE-5) INHIBITORS | OCEAN 1 806, LLC (US) | 2009-10-08 | — | — | WO | disclosed |
| EP-2091515-A2 | MODIFIED RELEASE ANALGESIC SUSPENSIONS | McNeil-PPC, Inc. (US) | 2009-08-26 | — | — | EP | disclosed |
| WO-2008064192-A2 | MODIFIED RELEASE ANALGESIC SUSPENSIONS | MCNEIL-PPC, INC. (US) | 2008-05-29 | — | — | WO | disclosed |
| US-20080118571-A1 | MODIFIED RELEASE ANALGESIC SUSPENSIONS | JOHNSON & JOHNSON CONSUMER INC. | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028480-A1 | ORODISPERSABLE FORMULATIONS OF PHOSPHODIESTERASE-5 (PDE-5) INHIBITORS | PDE5A, PDE3A, PDE12 | ALDH1A1 728/4885TSHR 3742/4885TDP1 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.