Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11770069 | 0.85 | ALDH1A1 (0.48) | ALDH1A1TP53TSHRHIF1ASMN1; SMN2 | |
| SCHEMBL11771216 | 0.84 | ALDH1A1 (0.54) | ALDH1A1TP53TSHRHIF1ASMN1; SMN2 | |
| SCHEMBL11771120 | 0.83 | ALDH1A1 (0.52) | ALDH1A1TP53TSHRHIF1ASMN1; SMN2 | |
| SCHEMBL11767227 | 0.83 | ALDH1A1 (0.55) | ALDH1A1TP53TSHRHIF1ASMN1; SMN2 | |
| SCHEMBL11768512 | 0.82 | TP53 (0.51) | ALDH1A1TP53TSHRHIF1ASMN1; SMN2 | |
| SCHEMBL11773346 | 0.82 | ALDH1A1 (0.54) | ALDH1A1TP53TSHRHIF1ASMN1; SMN2 | |
| SCHEMBL11769657 | 0.82 | ALDH1A1 (0.45) | ALDH1A1TP53TSHRHIF1ASMN1; SMN2 | |
| SCHEMBL11770902 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TP53TSHRHIF1ASMN1; SMN2 | |
| SCHEMBL11768611 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TP53TSHRHIF1ASMN1; SMN2 | |
| SCHEMBL11768694 | 0.76 | TP53 (0.52) | ALDH1A1TP53TSHRHIF1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940407-A | β-Adrenergic blocking agents in the 1,2,3-thiadiazole series | SYNTEX (U.S.A.) INC. (US) | 1976-02-24 | — | — | US | disclosed |