SCHEMBL11768545

SCHEMBL11768545

CCCCc1ccc(C(=O)O)c(-c2ccc(C#N)cc2)c1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTB4R2 Q9NPC1 2/20 0.53
TSHR P16473 1/20 0.52
HSD17B10 Q99714 1/20 0.52
PPARA Q07869 2/20 0.49
RARB P10826 5/20 0.48
RARA P10276 1/20 0.48
RARG P13631 1/20 0.48
BRS3 P32247 3/20 0.47
AKR1C2 P52895 1/20 0.46
AKR1C1 Q04828 1/20 0.46
PPARG P37231 1/20 0.46
KAT8 Q9H7Z6 2/20 0.46
SLC22A12 Q96S37 1/20 0.44
DHODH Q02127 1/20 0.44
METAP2 P50579 1/20 0.44
AGTR1 P30556 1/20 0.43
AGTR2 P50052 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6267448 0.96 TSHR (0.58) LTB4R2TSHRHSD17B10PPARARARB
SCHEMBL6269842 0.95 TSHR (0.60) LTB4R2TSHRHSD17B10PPARARARB
SCHEMBL3192071 0.94 TSHR (0.63) LTB4R2TSHRHSD17B10PPARARARB
Benzoic Acid SCHEMBL11341174 0.93 LTB4R2 (0.53) LTB4R2TSHRHSD17B10PPARARARB
SCHEMBL7512343 0.92 LTB4R2 (0.53) LTB4R2TSHRHSD17B10PPARARARB
SCHEMBL9755573 0.88 TSHR (0.65) LTB4R2TSHRHSD17B10PPARARARB
SCHEMBL5665946 0.88 RARB (0.59) PPARARARBRARARARGBRS3
SCHEMBL8048528 0.87 CYP2A6 (0.50) LTB4R2BRS3SLC22A12
SCHEMBL9148526 0.85 TSHR (0.45) LTB4R2TSHRHSD17B10PPARARARB
SCHEMBL5666124 0.85 RARB (0.64) PPARARARBRARARARGBRS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115322796-A Liquid crystal composition, moth eye film and preparation method thereof 上海先认新材料合伙企业(有限合伙) 2022-11-11 CN claimed
CN-115322796-B Liquid crystal composition, moth eye mask and preparation method of moth eye mask 上海先认新材料合伙企业(有限合伙) 2024-05-10 CN disclosed
CN-115301082-B Nanoscale microporous filter membrane, preparation method and application thereof 上海先认新材料合伙企业(有限合伙) 2024-01-16 CN disclosed
US-20230167339-A1 ADHESIVE COMPOSITION, ADHESIVE SHEET, AND JOINED BODY NITTO DENKO CORPORATION (JP) 2023-06-01 US disclosed
CN-115322796-A Liquid crystal composition, moth eye film and preparation method thereof 上海先认新材料合伙企业(有限合伙) 2022-11-11 CN disclosed
CN-115301082-A Nanoscale microporous filter membrane, preparation method and application thereof 上海先认新材料合伙企业(有限合伙) 2022-11-08 CN disclosed
US-4000084-A LIQUID CRYSTAL MIXTURES FOR ELECTRO-OPTICAL DISPLAY DEVICES HUGHES AIRCRAFT COMPANY (US) 1976-12-28 US disclosed
US-3957347-A Selectively variable circularly dichroic filtering method XEROX CORPORATION (US) 1976-05-18 US disclosed
US-3957346-A Method for altering elliptically polarized light XEROX CORPORATION (US) 1976-05-18 US disclosed
US-3957345-A Information transfer system XEROX CORPORATION (US) 1976-05-18 US disclosed
US-3957348-A Method for altering elliptically polarized light XEROX CORPORATION (US) 1976-05-18 US disclosed
US-3957344-A Information transfer system XEROX CORPORATION (US) 1976-05-18 US disclosed
US-3947184-A IMAGING METHOD XEROX CORPORATION (US) 1976-03-30 US disclosed