SCHEMBL6267448

SCHEMBL6267448

CCCCCc1ccc(C(=O)O)c(-c2ccc(C#N)cc2)c1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.58
HSD17B10 Q99714 1/20 0.58
PPARA Q07869 2/20 0.54
RARB P10826 10/20 0.53
RARA P10276 2/20 0.53
RARG P13631 1/20 0.53
LTB4R2 Q9NPC1 1/20 0.53
KAT8 Q9H7Z6 2/20 0.51
PPARG P37231 1/20 0.51
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPT P10636 1/20 0.47
MTOR P42345 1/20 0.47
KMT2A Q03164 1/20 0.47
AGTR1 P30556 1/20 0.44
AGTR2 P50052 1/20 0.44
BRS3 P32247 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6269842 0.99 TSHR (0.60) TSHRHSD17B10PPARARARBRARA
SCHEMBL3192071 0.98 TSHR (0.63) TSHRHSD17B10PPARARARBRARA
SCHEMBL11768545 0.96 LTB4R2 (0.53) TSHRHSD17B10PPARARARBRARA
SCHEMBL9755573 0.92 TSHR (0.65) TSHRHSD17B10PPARARARBRARA
SCHEMBL7512343 0.91 LTB4R2 (0.53) TSHRHSD17B10PPARARARBRARA
Benzoic Acid SCHEMBL11341174 0.90 LTB4R2 (0.53) TSHRHSD17B10PPARARARBRARA
SCHEMBL4908288 0.88 RARB (0.66) PPARARARBRARARARGKAT8
SCHEMBL9148526 0.87 TSHR (0.45) TSHRHSD17B10PPARARARBRARA
SCHEMBL5666124 0.87 RARB (0.64) PPARARARBRARARARGKAT8
SCHEMBL11135668 0.87 RARB (0.68) PPARARARBRARARARGKAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115322796-A Liquid crystal composition, moth eye film and preparation method thereof 上海先认新材料合伙企业(有限合伙) 2022-11-11 CN claimed
EP-1599562-A2 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES Nemoptic (FR) 2005-11-30 EP claimed
WO-2004077390-A2 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES NEMOPTIC (FR) 2004-09-10 WO claimed
CN-115322796-B Liquid crystal composition, moth eye mask and preparation method of moth eye mask 上海先认新材料合伙企业(有限合伙) 2024-05-10 CN disclosed
CN-115301082-B Nanoscale microporous filter membrane, preparation method and application thereof 上海先认新材料合伙企业(有限合伙) 2024-01-16 CN disclosed
CN-115322796-A Liquid crystal composition, moth eye film and preparation method thereof 上海先认新材料合伙企业(有限合伙) 2022-11-11 CN disclosed
CN-115301082-A Nanoscale microporous filter membrane, preparation method and application thereof 上海先认新材料合伙企业(有限合伙) 2022-11-08 CN disclosed
EP-0205261-B1 LIQUID CRYSTAL DROPLETS DISPERSED IN THIN FILMS OF UV-CURABLE POLYMERS GENERAL MOTORS CORPORATION (US) 1990-09-19 EP disclosed
US-4728547-A Liquid crystal droplets dispersed in thin films of UV-curable polymers GENERAL MOTORS CORPORATION (US) 1988-03-01 US disclosed
EP-0205261-A2 Liquid crystal droplets dispersed in thin films of UV-curable polymers GENERAL MOTORS CORPORATION (US) 1986-12-17 EP disclosed