Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11771660 | 0.85 | MRGPRX4 (0.41) | MRGPRX4NR4A2KMT2AMEN1ENPP2 | |
| SCHEMBL850085 | 0.82 | MEN1 (0.72) | MRGPRX4NR4A2KMT2AMEN1SRD5A2 | |
| SCHEMBL29207020 | 0.81 | GRM4 (0.62) | MRGPRX4KMT2AMEN1MAPTNPC1 | |
| SCHEMBL29434530 | 0.79 | MRGPRX4 (0.47) | MRGPRX4NR4A2KMT2AMEN1MAPT | |
| SCHEMBL22530375 | 0.79 | MRGPRX4 (0.47) | MRGPRX4NR4A2KMT2AMEN1MAPT | |
| SCHEMBL25183205 | 0.79 | MRGPRX4 (0.45) | MRGPRX4NR4A2KMT2AMEN1ENPP2 | |
| SCHEMBL11773503 | 0.78 | KMT2A (0.57) | MRGPRX4KMT2AMEN1MAPTNPC1 | |
| SCHEMBL5839185 | 0.77 | NR4A2 (0.66) | MRGPRX4NR4A2KMT2AMEN1MAPT | |
| SCHEMBL13699188 | 0.76 | PLA2G2A (0.53) | MRGPRX4NR4A2KMT2AMEN1 | |
| SCHEMBL25173367 | 0.75 | MRGPRX4 (0.44) | MRGPRX4NR4A2KMT2AMEN1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953595-A | Substituted benzoic acid hypolipemic agents | PFIZER INC. (US) | 1976-04-27 | — | — | US | disclosed |