Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 6/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.38 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11785790 | 1.00 | LTB4R (0.51) | LTB4RAKR1B1MAOAMAOBTHRA | |
| SCHEMBL11766984 | 1.00 | LTB4R (0.51) | LTB4RAKR1B1MAOAMAOBTHRA | |
| SCHEMBL11771871 | 1.00 | LTB4R (0.51) | LTB4RAKR1B1MAOAMAOBTHRA | |
| SCHEMBL11770659 | 0.93 | LTB4R (0.51) | LTB4RAKR1B1THRATHRB | |
| SCHEMBL11770210 | 0.93 | LTB4R (0.51) | LTB4RAKR1B1THRATHRB | |
| SCHEMBL11769092 | 0.92 | LTB4R (0.51) | LTB4RAKR1B1THRATHRBLTB4R2 | |
| SCHEMBL11768257 | 0.92 | LTB4R (0.51) | LTB4RAKR1B1THRATHRBLTB4R2 | |
| SCHEMBL11767836 | 0.92 | LTB4R (0.51) | LTB4RAKR1B1THRATHRBLTB4R2 | |
| SCHEMBL11765899 | 0.92 | LTB4R (0.61) | LTB4RAKR1B1LTB4R2TTRS1PR3 | |
| SCHEMBL11766632 | 0.92 | LTB4R (0.61) | LTB4RAKR1B1LTB4R2TTRS1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3989721-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-11-02 | — | — | US | disclosed |
| US-3989720-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-11-02 | — | — | US | disclosed |
| US-3988352-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-10-26 | — | — | US | disclosed |
| US-3979414-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-09-07 | — | — | US | disclosed |
| US-3965115-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-06-22 | — | — | US | disclosed |
| US-3963753-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-06-15 | — | — | US | disclosed |
| US-3963752-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-06-15 | — | — | US | disclosed |