SCHEMBL117692

SCHEMBL117692

FC(F)(F)c1ccccc1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.48
TSHR P16473 2/20 0.47
LMNA P02545 2/20 0.47
HSD11B1 P28845 1/20 0.47
ALDH1A1 P00352 2/20 0.43
POLB P06746 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CYP19A1 P11511 1/20 0.42
AR P10275 1/20 0.42
P2RX7 Q99572 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
IDO1 P14902 3/20 0.40
KCNJ5 P48544 1/20 0.40
KCNJ3 P48549 1/20 0.40
PYCR1 P32322 1/20 0.40
HTR3E A5X5Y0 1/20 0.39
HTR3B O95264 1/20 0.39
HTR3A P46098 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5966718 1.00 KCNN4 (0.48) KCNN4TSHRLMNAHSD11B1ALDH1A1
SCHEMBL29467226 1.00 KCNN4 (0.48) KCNN4TSHRLMNAHSD11B1ALDH1A1
SCHEMBL5607381 0.97 KCNN4 (0.46) KCNN4TSHRLMNAHSD11B1ALDH1A1
SCHEMBL28034993 0.97 KCNN4 (0.46) KCNN4TSHRLMNAHSD11B1ALDH1A1
SCHEMBL29057192 0.97 KCNN4 (0.46) KCNN4TSHRLMNAHSD11B1ALDH1A1
Benzene SCHEMBL29136712 0.97 KCNN4 (0.52) KCNN4TSHRLMNAHSD11B1ALDH1A1
Ammonia Solution, Strong SCHEMBL15562823 0.97 KCNN4 (0.46) KCNN4TSHRLMNAHSD11B1ALDH1A1
SCHEMBL4463108 0.97 KCNN4 (0.46) KCNN4TSHRLMNAHSD11B1ALDH1A1
SCHEMBL27901573 0.95 KCNN4 (0.45) KCNN4TSHRLMNAHSD11B1ALDH1A1
Methyl Alcohol SCHEMBL28261605 0.93 HSD11B1 (0.47) KCNN4TSHRLMNAHSD11B1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2539 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12122935-B2 Curable organopolysiloxane composition for forming film and production method for organopolysiloxane cured product film DOW TORAY CO., LTD. (JP) 2024-10-22 US claimed
WO-2024134508-A1 HYDROPHOBIC AND SUPERHYDROPHOBIC COATINGS AND METHOD OF MAKING AT ROOM TEMPERATURE TECHNOLOGY INNOVATION INSTITUTE - SOLE PROPRIETORSHIP LLC (AE) 2024-06-27 WO claimed
CN-118119583-A Method for producing fluorine-containing aromatic compound 大金工业株式会社 2024-05-31 CN claimed
CN-118084728-A Preparation method of p-trifluoromethyl benzonitrile 杭州柏榆生物科技有限公司 2024-05-28 CN claimed
EP-3676311-B1 NOVEL (PER)FLUOROPOLYETHER POLYMERS AND USE THEREOF SOLVAY SPECIALTY POLYMERS IT (IT) 2023-10-18 EP claimed
US-20220396533-A1 METHOD FOR PREPARING DEUTERATED ORGANIC COMPOUNDS ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2022-12-15 US claimed
CN-115403435-A Process for preparing deuterated organic compounds 罗门哈斯电子材料韩国有限公司 2022-11-29 CN claimed
US-11485809-B2 Method for producing amido-methylated vinyl-aromatic bead polymers LANXESS DEUTSCHLAND GMBH (DE) 2022-11-01 US claimed
CN-115028575-A Synthetic method of 2-chloro-6-trichloromethylpyridine 内蒙古佳瑞米精细化工有限公司 2022-09-09 CN claimed
CN-115011120-A Fishing line wheel prepared from high-molecular wear-resistant material and preparation method thereof 安徽博佳钓具有限公司 2022-09-06 CN claimed
EP-0145334-A2 Benzaldehyde derivative and process for its preparation Pfizer Limited (GB) 1985-06-19 EP claimed
EP-0054464-B1 PROCESS FOR THE PREPARATION OF ORTHO-TRIFLUOROMETHYL ANILINE RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-11-21 EP claimed
US-4470930-A Preparation of nuclear chlorinated aromatic compounds OCCIDENTAL CHEMICAL CORPORATION (US) 1984-09-11 US claimed
EP-0074069-A1 Process for preparing chlorotrifluoromethylbenzene Daikin Kogyo Co., Ltd. (JP) 1983-03-16 EP claimed
EP-0054464-A1 Process for the preparation of ortho-trifluoromethyl aniline RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1982-06-23 EP claimed
EP-0004447-B1 PREPARATION OF TRIFLUOROMETHYLPHENOLS AND NOVEL TRIFLUOROMETHYLPHENYL BENZYL ETHER INTERMEDIATES ELI LILLY AND COMPANY (US) 1981-12-02 EP claimed
EP-0004447-A2 Preparation of trifluoromethylphenols and novel trifluoromethylphenyl benzyl ether intermediates ELI LILLY AND COMPANY (US) 1979-10-03 EP claimed
US-4136019-A ORGANIC TRIFLUORO COMPOUND AS SELECTIVITY AGENT, FATTY ACID COLLECTOR UNITED STATES BORAX & CHEMICAL CORP. (US) 1979-01-23 US claimed
US-4059610-A Process for preparing isocyanic acid derivatives KAO SOAP CO., LTD. (JA) 1977-11-22 US claimed
US-3961023-A Process for the production of cyanogen chloride and hydrogen chloride DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1976-06-01 US claimed