Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13140896 | 0.84 | DHFR (0.57) | DHFRHSD11B1KDM4CMEN1KMT2A | |
| SCHEMBL31052241 | 0.84 | DHFR (0.60) | DHFRHSD11B1KDM4CALDH1A1CA1 | |
| SCHEMBL29646513 | 0.84 | DHFR (0.57) | DHFRHSD11B1KDM4CMEN1KMT2A | |
| SCHEMBL7234370 | 0.84 | DHFR (0.57) | DHFRHSD11B1KDM4CALDH1A1MAPK1 | |
| SCHEMBL7772717 | 0.84 | DHFR (0.57) | DHFRHSD11B1KDM4CALDH1A1MAPK1 | |
| SCHEMBL25219553 | 0.84 | DHFR (0.60) | DHFRHSD11B1KDM4CALDH1A1CA1 | |
| SCHEMBL10182225 | 0.84 | DHFR (0.57) | DHFRHSD11B1KDM4CMEN1KMT2A | |
| SCHEMBL2464134 | 0.84 | DHFR (0.57) | DHFRHSD11B1KDM4CMEN1KMT2A | |
| SCHEMBL21257491 | 0.84 | DHFR (0.57) | DHFRHSD11B1KDM4CMEN1KMT2A | |
| SCHEMBL3184997 | 0.83 | DHFR (0.53) | DHFRHSD11B1KDM4CMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940407-A | β-Adrenergic blocking agents in the 1,2,3-thiadiazole series | SYNTEX (U.S.A.) INC. (US) | 1976-02-24 | — | — | US | disclosed |