Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11651852 | 1.00 | PLCG1 (0.72) | PLCG1L3MBTL1ALDH1A1POLBMAPT | |
| SCHEMBL11770430 | 0.94 | PLCG1 (0.74) | PLCG1L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL11770424 | 0.94 | PLCG1 (0.74) | PLCG1L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL11772203 | 0.92 | PLCG1 (0.72) | PLCG1L3MBTL1ALDH1A1TDP1MAPK1 | |
| SCHEMBL11772200 | 0.92 | PLCG1 (0.72) | PLCG1L3MBTL1ALDH1A1TDP1MAPK1 | |
| SCHEMBL10778893 | 0.92 | PLCG1 (0.82) | PLCG1L3MBTL1ALDH1A1TDP1MAPK1 | |
| SCHEMBL9180696 | 0.92 | PLCG1 (0.82) | PLCG1L3MBTL1ALDH1A1TDP1MAPK1 | |
| SCHEMBL11541672 | 0.92 | PLCG1 (0.82) | PLCG1L3MBTL1ALDH1A1TDP1MAPK1 | |
| SCHEMBL11278886 | 0.92 | PLCG1 (0.82) | PLCG1L3MBTL1ALDH1A1TDP1MAPK1 | |
| SCHEMBL9186607 | 0.92 | PLCG1 (0.82) | PLCG1L3MBTL1ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3972774-A | BY AN ESTERASE ENZYME FROM BACILLUS | ELI LILLY AND COMPANY (US) | 1976-08-03 | — | — | US | disclosed |