Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11772203 | 1.00 | PLCG1 (0.72) | PLCG1L3MBTL1ALDH1A1MAPK1CTDSP1 | |
| SCHEMBL11770430 | 0.94 | PLCG1 (0.74) | PLCG1L3MBTL1ALDH1A1MAPK1CTDSP1 | |
| SCHEMBL11770424 | 0.94 | PLCG1 (0.74) | PLCG1L3MBTL1ALDH1A1MAPK1CTDSP1 | |
| SCHEMBL11769717 | 0.92 | PLCG1 (0.72) | PLCG1L3MBTL1ALDH1A1MAPK1CTDSP1 | |
| SCHEMBL11651852 | 0.92 | PLCG1 (0.72) | PLCG1L3MBTL1ALDH1A1MAPK1CTDSP1 | |
| SCHEMBL10778893 | 0.92 | PLCG1 (0.82) | PLCG1L3MBTL1ALDH1A1MAPK1CTDSP1 | |
| SCHEMBL9186607 | 0.92 | PLCG1 (0.82) | PLCG1L3MBTL1ALDH1A1MAPK1CTDSP1 | |
| SCHEMBL11541672 | 0.92 | PLCG1 (0.82) | PLCG1L3MBTL1ALDH1A1MAPK1CTDSP1 | |
| SCHEMBL11278886 | 0.92 | PLCG1 (0.82) | PLCG1L3MBTL1ALDH1A1MAPK1CTDSP1 | |
| SCHEMBL9180696 | 0.92 | PLCG1 (0.82) | PLCG1L3MBTL1ALDH1A1MAPK1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3972774-A | BY AN ESTERASE ENZYME FROM BACILLUS | ELI LILLY AND COMPANY (US) | 1976-08-03 | — | — | US | disclosed |