Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11768694 | 0.85 | TP53 (0.52) | TDP1ALDH1A1TP53TSHRMEN1 | |
| SCHEMBL11770036 | 0.82 | ALDH1A1 (0.48) | TDP1ALDH1A1TP53TSHRMEN1 | |
| SCHEMBL11766186 | 0.80 | TDP1 (0.46) | TDP1ALDH1A1TP53TSHRMEN1 | |
| SCHEMBL11771508 | 0.80 | TDP1 (0.44) | TDP1ALDH1A1TP53TSHRMEN1 | |
| SCHEMBL11771028 | 0.79 | ALDH1A1 (0.45) | TDP1ALDH1A1TP53TSHRMEN1 | |
| SCHEMBL11768964 | 0.79 | TDP1 (0.54) | TDP1ALDH1A1TP53TSHRMEN1 | |
| SCHEMBL11768372 | 0.79 | TDP1 (0.54) | TDP1ALDH1A1TP53TSHRMEN1 | |
| SCHEMBL11770592 | 0.78 | ALDH1A1 (0.44) | TDP1ALDH1A1TP53TSHRMEN1 | |
| SCHEMBL11770778 | 0.78 | ALDH1A1 (0.46) | TDP1ALDH1A1TP53TSHRMEN1 | |
| Water SCHEMBL11032953 | 0.75 | TDP1 (0.68) | TDP1ALDH1A1TP53TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940407-A | β-Adrenergic blocking agents in the 1,2,3-thiadiazole series | SYNTEX (U.S.A.) INC. (US) | 1976-02-24 | — | — | US | disclosed |