SCHEMBL11769725

SCHEMBL11769725

C=CCNc1c(C)ccc(N)c1C

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
CCNA2 P20248 1/20 0.33
CDK2 P24941 1/20 0.33
HPGD P15428 1/20 0.33
CYP3A4 P08684 2/20 0.31
TSHR P16473 1/20 0.31
PIK3CA P42336 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
KDM4E B2RXH2 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C19 P33261 1/20 0.30
KLK7 P49862 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20019398 0.77 CYP3A4 (0.41) HPGDCYP3A4TSHRPIK3CAKDM4E
SCHEMBL11245637 0.75 GAA (0.41) CA12CA1CA2CA9HPGD
SCHEMBL15928718 0.71 CYP3A4 (0.45) CA12CA1CA2CA9CCNA2
SCHEMBL15928717 0.71 CA12 (0.46) CA12CA1CA2CA9CCNA2
Hydrochloric Acid SCHEMBL11428328 0.70 TLR8 (0.39) KDM4E
SCHEMBL16191405 0.70 CYP3A4 (0.40) HPGDCYP3A4TSHRPIK3CAKDM4E
SCHEMBL3380445 0.69 CA12 (0.36) CA12CA1CA2CA9
SCHEMBL24489437 0.69 TSHR (0.44) HPGDTSHRKDM4ECYP1A2
SCHEMBL22025923 0.69
SCHEMBL28275294 0.69 CYP3A4 (0.39) HPGDCYP3A4TSHRPIK3CAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4032482-A FROM A POLY-N-SUBSTITUTED POLYAMINE OR POLYALKYLENIMINE-EPOXY COMPOUND PREPOLYMER MIYOSHI YUSHI KABUSHIKI KAISHA (JA) 1977-06-28 US disclosed