SCHEMBL3380445

SCHEMBL3380445

C=CCNc1ccc(N)c(N)c1NCC=C

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
CA14 Q9ULX7 1/20 0.36
HCAR3 P49019 2/20 0.34
RRM2 P31350 1/20 0.31
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3375185 0.76 RRM2 (0.38) CA12CA1CA2CA9CA14
SCHEMBL5549248 0.74 RRM2 (0.38) CA12CA1CA2CA9CA14
SCHEMBL9812130 0.72 ALDH1A1 (0.37) CA12CA1CA2CA9CA14
SCHEMBL476574 0.71 MAPT (0.42) CA12CA1CA2CA9CA14
SCHEMBL11769725 0.69 CA12 (0.35) CA12CA1CA2CA9
SCHEMBL12502010 0.68 HCAR3 (0.35) CA12CA1CA2CA9CA14
SCHEMBL16831152 0.67 CA12 (0.37) CA12CA1CA2CA9CA14
SCHEMBL9220813 0.67 ALDH1A1 (0.44) CA12CA1CA2CA9CA14
SCHEMBL4784858 0.66 ALDH1A1 (0.44) CA12CA1CA2CA9CA14
SCHEMBL15823268 0.66 ALDH1A1 (0.50) CA12CA1CA2CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9943809-B2 Solvent resistant thin film composite membrane and its preparation KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2018-04-17 US claimed
US-20170065937-A1 SOLVENT RESISTANT THIN FILM COMPOSITE MEMBRANE AND ITS PREPARATION KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2017-03-09 US claimed
US-5693227-A POLYMERIZATION OF MOLECULES HAVING ELECTROPHILIC AND NUCLEOPHILIC SUBSTITUENTS ON THE SAME OR DIFFERENT MOLECULES; REGENERATION OF AMINOPYRIDINE CATALYSTS IONICS, INCORPORATED (US) 1997-12-02 US claimed
US-12036515-B2 Thin-film composite membrane and methods of making and using the same THE PENN STATE RESEARCH FOUNDATION (PA) 2024-07-16 US disclosed
US-20210370240-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME THE PENN STATE RESEARCH FOUNDATION 2021-12-02 US disclosed
EP-3860743-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME The Penn State Research Foundation (US) 2021-08-11 EP disclosed
WO-2020072594-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME THE PENN STATE RESEARCH FOUNDATION (US) 2020-04-09 WO disclosed
US-9943809-B2 Solvent resistant thin film composite membrane and its preparation KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2018-04-17 US disclosed
US-20170065937-A1 SOLVENT RESISTANT THIN FILM COMPOSITE MEMBRANE AND ITS PREPARATION KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2017-03-09 US disclosed
US-7727434-B2 Membranes and methods of treating membranes GENERAL ELECTRIC COMPANY (US) 2010-06-01 US disclosed
US-20070039874-A1 Membranes and methods of treating membranes GENERAL ELECTRIC COMPANY 2007-02-22 US disclosed
US-5693227-A POLYMERIZATION OF MOLECULES HAVING ELECTROPHILIC AND NUCLEOPHILIC SUBSTITUENTS ON THE SAME OR DIFFERENT MOLECULES; REGENERATION OF AMINOPYRIDINE CATALYSTS IONICS, INCORPORATED (US) 1997-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12036515-B2 Thin-film composite membrane and methods of making and using the same PORCN, MLEC, FLOT1 CA12 1547/4885CA1 2322/4885CA2 3089/4885
US-20210370240-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME PORCN, MLEC, FLOT1 CA12 1547/4885CA1 2322/4885CA2 3089/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.