Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 2/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5808127 | 0.82 | LMNA (0.55) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL13428746 | 0.78 | LMNA (0.50) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL10594834 | 0.78 | LMNA (0.50) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL1935211 | 0.78 | LMNA (0.50) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL7603205 | 0.75 | LMNA (0.46) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL10930855 | 0.75 | LMNA (0.46) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL6925686 | 0.74 | LMNA (0.44) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL14244550 | 0.74 | LMNA (0.44) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL385724 | 0.73 | LMNA (0.55) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL1179123 | 0.73 | LMNA (0.55) | LMNAKMT2AMEN1THRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4034043-A | PRODUCTION OF 2-AMINO-5-CHLORO-TOLUENE HYDROCHLORIDE | CIBA-GEIGY CORPORATION (US) | 1977-07-05 | — | — | US | disclosed |