Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 4/20 | 0.55 |
| ▸ | NOX1 | Q9Y5S8 | 12/20 | 0.55 |
| ▸ | GAA | P10253 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | BCHE | P06276 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8941201 | 0.90 | NOX1 (0.55) | SNCANOX1GAAMAPTMEN1 | |
| SCHEMBL10889794 | 0.84 | SNCA (0.55) | SNCANOX1GAAMAPTMEN1 | |
| SCHEMBL11770566 | 0.83 | SNCA (0.51) | SNCANOX1GAAMAPTMEN1 | |
| SCHEMBL14146529 | 0.82 | NOX1 (0.72) | SNCANOX1GAAMAPTMEN1 | |
| Phenothiazine SCHEMBL31210229 | 0.79 | NOX1 (0.68) | SNCANOX1GAAMAPTMEN1 | |
| Phenothiazine SCHEMBL4937245 | 0.76 | NOX1 (0.94) | SNCANOX1GAAMAPTMEN1 | |
| Phenothiazine SCHEMBL28015533 | 0.75 | NOX1 (0.74) | SNCANOX1GAAMAPTMEN1 | |
| Phenothiazine SCHEMBL38662173 | 0.75 | NOX1 (0.74) | SNCANOX1GAAMAPTMEN1 | |
| SCHEMBL9185969 | 0.74 | NOX1 (0.55) | SNCANOX1GAAMAPTMEN1 | |
| SCHEMBL11744639 | 0.74 | NOX1 (0.55) | SNCANOX1GAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3961055-A | ANTIEMETIC AGENTS | RHONE-POULENC INDUSTRIES (FR) | 1976-06-01 | — | — | US | disclosed |