Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 13/20 | 0.55 |
| ▸ | GAA | P10253 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | SNCA | P37840 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | CYBB | P04839 | 2/20 | 0.55 |
| ▸ | NOX3 | Q9HBY0 | 2/20 | 0.55 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | BCHE | P06276 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11770232 | 0.90 | SNCA (0.55) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL9185969 | 0.84 | NOX1 (0.55) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL11744639 | 0.84 | NOX1 (0.55) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL9186453 | 0.84 | NOX1 (0.55) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL561135 | 0.83 | NOX1 (0.51) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL9185974 | 0.83 | NOX1 (0.54) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL6491876 | 0.79 | NOX1 (0.48) | NOX1GAAMAPTMEN1KMT2A | |
| Phenothiazine SCHEMBL31210229 | 0.79 | NOX1 (0.68) | NOX1GAAMAPTMEN1KMT2A | |
| Phenothiazine SCHEMBL4937245 | 0.76 | NOX1 (0.94) | NOX1GAAMAPTMEN1KMT2A | |
| Phenothiazine SCHEMBL38662173 | 0.75 | NOX1 (0.74) | NOX1GAAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111039898-B | Preparation method of metopimazine intermediate | 暨明医药科技（苏州）有限公司 | 2021-12-24 | — | — | CN | claimed |
| CN-109053716-B | Novel process for preparing metopimazine | 暨明医药科技（苏州）有限公司 | 2021-01-08 | — | — | CN | claimed |
| CN-111039898-A | Preparation method of metopimazine intermediate | 暨明医药科技（苏州）有限公司 | 2020-04-21 | — | — | CN | claimed |
| US-5486582-A | Polymer scale preventive process using a coating of chitosan salt and phenothiazine | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-01-23 | — | — | US | claimed |
| CN-111039898-B | Preparation method of metopimazine intermediate | 暨明医药科技（苏州）有限公司 | 2021-12-24 | — | — | CN | disclosed |
| CN-111039898-B | Preparation method of metopimazine intermediate | 暨明医药科技（苏州）有限公司 | 2021-12-24 | — | — | CN | disclosed |
| CN-109053716-B | Novel process for preparing metopimazine | 暨明医药科技（苏州）有限公司 | 2021-01-08 | — | — | CN | disclosed |
| CN-111039898-A | Preparation method of metopimazine intermediate | 暨明医药科技（苏州）有限公司 | 2020-04-21 | — | — | CN | disclosed |
| CN-111039898-A | Preparation method of metopimazine intermediate | 暨明医药科技（苏州）有限公司 | 2020-04-21 | — | — | CN | disclosed |
| CN-105837528-A | Preparation method of 2- (methylsulfonyl) -10H-phenothiazine | 大连理工大学 | 2016-08-10 | — | — | CN | disclosed |
| CN-105837528-A | Preparation method of 2- (methylsulfonyl) -10H-phenothiazine | 大连理工大学 | 2016-08-10 | — | — | CN | disclosed |
| US-5486582-A | Polymer scale preventive process using a coating of chitosan salt and phenothiazine | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-01-23 | — | — | US | disclosed |