Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 2/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11772311 | 0.83 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2TSHRTP53CASP1 | |
| SCHEMBL2334381 | 0.82 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2TSHRTP53CASP1 | |
| SCHEMBL6299980 | 0.82 | EPHX1 (0.53) | ATML3MBTL1EPHX1GAA | |
| SCHEMBL22473881 | 0.80 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2TSHRTP53CASP1 | |
| SCHEMBL3927953 | 0.79 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2TSHRTP53CASP1 | |
| SCHEMBL4608397 | 0.79 | KDM4E (0.49) | ALDH1A1SMN1; SMN2TSHRTP53CASP1 | |
| SCHEMBL27853748 | 0.78 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2TSHRTP53CASP1 | |
| SCHEMBL24252677 | 0.78 | EPHX1 (0.42) | ALDH1A1SMN1; SMN2KDM4EATML3MBTL1 | |
| SCHEMBL3282467 | 0.77 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2TSHRTP53CASP1 | |
| SCHEMBL8482188 | 0.77 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2TSHRTP53CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953595-A | Substituted benzoic acid hypolipemic agents | PFIZER INC. (US) | 1976-04-27 | — | — | US | disclosed |