SCHEMBL11770477

SCHEMBL11770477

CCCCCCCCCCCCCCCCCCNc1nc(N2C(C)(C)CCCC2(C)C)nc(N2C(C)(C)CC(N)CC2(C)C)n1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
DNM2 P50570 7/20 0.33
KCNH3 Q9ULD8 2/20 0.33
MERTK Q12866 1/20 0.32
CAMK2D Q13557 1/20 0.32
EHMT2 Q96KQ7 2/20 0.31
EHMT1 Q9H9B1 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11729632 1.00 KMT2A (0.37) KMT2AMEN1LMNADNM2KCNH3
SCHEMBL11722963 0.92 KMT2A (0.42) KMT2AMEN1LMNADNM2KCNH3
SCHEMBL11726644 0.86 KMT2A (0.49) KMT2AMEN1LMNADNM2KCNH3
SCHEMBL11725328 0.85 KMT2A (0.35) KMT2AMEN1LMNADNM2KCNH3
SCHEMBL11725213 0.85 MEN1 (0.35) KMT2AMEN1LMNA
SCHEMBL8491805 0.79
SCHEMBL11724209 0.79
SCHEMBL11725953 0.79 LTA4H (0.33)
SCHEMBL11723869 0.79 LTA4H (0.33)
SCHEMBL11725556 0.79 SPHK1 (0.39) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4028334-A STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1977-06-07 US disclosed